Inflammation and necrosis syndrome is associated with alterations in blood and metabolism in pigs.

ABSTRACT:

Background

Swine inflammation and necrosis syndrome (SINS) can lead to significant clinical alterations at tail, ears, claws and other parts of the body in suckling piglets, weaners and fatteners. Clinical findings are associated with vasculitis, intima proliferation and thrombosis. The syndrome can be found in newborns, indicating a primarily endogenous aetiology. It has been hypothesized that SINS is triggered by gut-derived microbial-associated molecular patterns, causing derangements in liver metabolism and activity of peripheral white blood cells involving inflammation and blood haemostasis. In order to characterize these metabolic derangements of SINS for the first time, red and white blood counts, parameters of blood haemostasis, serum metabolites and acute phase proteins in

SUBMITTER: Loewenstein F 

PROVIDER: S-EPMC8767723 | biostudies-literature | 2022 Jan

REPOSITORIES: biostudies-literature