Acute hepatitis E virus superinfection increases mortality in patients with cirrhosis.

ABSTRACT:

Background

Although acute hepatitis E is not fatal in healthy individuals, it is unclear whether hepatitis E superinfection increases the mortality in patients with pre-existing liver disease. Thus, we investigated the prognosis of patients with acute hepatitis E according to their cirrhosis diagnosis, and the prognosis according to the development of acute-on-chronic liver failure (ACLF) in patients with cirrhosis and chronic liver disease (CLD).

Methods

This study included 74 consecutive patients who were diagnosed with acute viral hepatitis E between January 2007 and December 2019. Of them, 39 patients without CLD, 13 patients with non-cirrhotic CLD, and 22 patients with cirrhotic CLD were analyzed.

Results

Among the 74 patients with HEV infection, 7 (9.5%) died wi

SUBMITTER: Choi JW 

PROVIDER: S-EPMC8767750 | biostudies-literature | 2022 Jan

REPOSITORIES: biostudies-literature