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Multiple environmental exposures in early-life and allergy-related outcomes in childhood.


ABSTRACT:

Introduction

Early onset and high prevalence of allergic diseases result in high individual and socio-economic burdens. Several studies provide evidence for possible effects of environmental factors on allergic diseases, but these are mainly single-exposure studies. The exposome provides a novel holistic approach by simultaneously studying a large set of exposures. The aim of the study was to evaluate the association between a broad range of prenatal and childhood environmental exposures and allergy-related outcomes in children.

Material and methods

Analyses of associations between 90 prenatal and 107 childhood exposures and allergy-related outcomes (last 12 months: rhinitis and itchy rash; ever: doctor-diagnosed eczema and food allergy) in 6-11 years old children (n = 1270)

SUBMITTER: Granum B 

PROVIDER: S-EPMC8768577 | biostudies-literature | 2020 Nov

REPOSITORIES: biostudies-literature