Prophylactic versus therapeutic dose anticoagulation effects on survival among critically ill patients with COVID-19.

ABSTRACT:

Introduction

Although patients with severe COVID-19 are known to be at high risk of developing thrombotic events, the effects of anticoagulation (AC) dose and duration on in-hospital mortality in critically ill patients remain poorly understood and controversial. The goal of this study was to investigate survival of critically ill COVID-19 patients who received prophylactic or therapeutic dose AC and analyze the mortality rate with respect to detailed demographic and clinical characteristics.

Materials and methods

We conducted a retrospective, observational study of critically ill COVID-19 patients admitted to the ICU at Stony Brook University Hospital in New York who received either prophylactic (n = 158) or therapeutic dose AC (n = 153). Primary outcome was in-hospital dea

SUBMITTER: Hoogenboom WS 

PROVIDER: S-EPMC8769345 | biostudies-literature | 2022

REPOSITORIES: biostudies-literature