Non-nucleoside structured compounds with antiviral activity-past 10 years (2010-2020).

ABSTRACT: Nucleosides and their derivatives are a well-known and well-described class of compounds with antiviral activity. Currently, in the era of the COVID-19 pandemic, scientists are also looking for compounds not related to nucleosides with antiviral properties. This review aims to provide an overview of selected synthetic antiviral agents not associated to nucleosides developed against human viruses and introduced to preclinical and clinical trials as well as drugs approved for antiviral therapy over the last 10 years. The article describes for the first time the wide classification of such antiviral drugs and drug candidates and briefly summarizes the biological target and clinical applications of the compounds. The described compounds are arranged according to the antiviral mechanism of acti

SUBMITTER: Denel-Bobrowska M 

PROVIDER: S-EPMC8769541 | biostudies-literature | 2022 Mar

REPOSITORIES: biostudies-literature