Prognostic value of baseline imaging and clinical features in patients with advanced hepatocellular carcinoma.

ABSTRACT:

Aims

To investigate the prognostic value of baseline imaging features for overall survival (OS) and liver decompensation (LD) in patients with hepatocellular carcinoma (HCC).

Design

Patients with advanced HCC from the SORAMIC trial were evaluated in this post hoc analysis. Several radiological imaging features were collected from baseline computed tomography (CT) and magnetic resonance imaging (MRI) imaging, besides clinical values. The prognostic value of these features for OS and LD (grade 2 bilirubin increase) was quantified with univariate Cox proportional hazard models and multivariate Least Absolute Shrinkage and Selection Operator (LASSO) regression.

Results

Three hundred and seventy-six patients were included in this study. The treatment arm was not correlated

SUBMITTER: Ocal O 

PROVIDER: S-EPMC8770679 | biostudies-literature | 2022 Feb

REPOSITORIES: biostudies-literature