Citrus Consumption and Risk of Non-Melanoma Skin Cancer in the UK Biobank.

ABSTRACT: Background: Non-melanoma skin cancer (NMSC) incidence has been dramatically increasing worldwide. Psoralen, a known photocarcinogen, is naturally abundant in citrus products, leading to the hypothesis that high citrus consumption may increase NMSC risk.Methods: We fitted age- and multivariable-adjusted logistic regression models to evaluate the association between citrus consumption and NMSC risk among 197,372 UKBB participants. A total of 9,613 NMSC cases were identified using International Classification of Disease 10 codes. Citrus consumption data were collected via five rounds of 24-hour recall questionnaires.Results: We found no association between high total citrus consumption and NMSC risk, although a slightly elevated NMSC risk was observed among participants w

SUBMITTER: Marley AR 

PROVIDER: S-EPMC8770706 | biostudies-literature | 2022

REPOSITORIES: biostudies-literature