Characterization of One-Year Progression of Risk Phenotypes of Diabetic Retinopathy.

ABSTRACT:

Introduction

We characterized the progression of different diabetic retinopathy (DR) phenotypes in type 2 diabetes (T2D).

Methods

A prospective longitudinal cohort study (CORDIS, NCT03696810) was conducted with three visits (baseline, 6 months, and 1 year). Demographic and systemic data included age, sex, diabetes duration, lipid profile, and hemoglobin A1c (HbA1c). Ophthalmological examinations included best-corrected visual acuity (BCVA), color fundus photography (CFP), and optical coherence tomography (OCT and OCTA). Phenotype classification was performed at the 6-month visit based on microaneurysm turnover (MAT, on CFP) and central retinal thickness (CRT, on OCT). Only risk phenotypes B (MAT < 6 and increased CRT) and C (MAT ≥ 6 with or without increased CRT) were includ

SUBMITTER: Ribeiro L 

PROVIDER: S-EPMC8770718 | biostudies-literature | 2022 Feb

REPOSITORIES: biostudies-literature