Features and evolution of patients with systemic amyloidosis and cardiac involvement

ABSTRACT:

Objective

To estimate the prevalence of cardiac amyloidosis in patients with systemic amyloidosis. Compare survival rates based on whether they show cardiac involvement.

Methods

A retrospective cohort study of patients with systemic amyloidosis from the Institutional Amyloidosis Registry of the Hospital Italian of Buenos Aires from 2010 to 2019. Heart involvement is considered to be the presence of symptoms and/or images consistent with amyloidosis, and there is no other reason to explain it. All deaths due to causes were evaluated. The survival rate was estimated by Kaplan-Meier. Cox regression model was used to evaluate factors related to mortality. Heart transplantation was evaluated in a competitive risk regression model.

Results

The prevalence of heart involvemen

SUBMITTER: Carretero M 

PROVIDER: S-EPMC8771037 | biostudies-literature | 2022 Jan

REPOSITORIES: biostudies-literature