Longitudinal changes in HDL-cholesterol concentration are associated with different risk factors in primiparous and nulliparous young women: The NHLBI Growth and Health Study (NGHS).

ABSTRACT:

Background

Previous studies report that first pregnancy is associated with persistent decreases in HDL-cholesterol (HDL-C) concentrations.

Objective

This study evaluated factors associated with declines in HDL-C concentration in parous and nulliparous young women.

Methods

This study leverages data from African-American and white women from the NHLBI Growth and Health Study. Parity-related changes in lipids, BMI and percent body fat were assessed longitudinally. A subset of primiparous and nulliparous women with paired lipid measurements were analyzed regarding changes in HDL-C concentrations.

Results

Among 870 women in longitudinal analyses, African-American women had higher parity (p<0.0001), with baseline measurements of each parity group being similar. HDL-C

SUBMITTER: Woollett LA 

PROVIDER: S-EPMC8771461 | biostudies-literature | 2021 May-Jun

REPOSITORIES: biostudies-literature