Quantification of the Peripapillary Microvasculature in Eyes with Glaucomatous Paracentral Visual Field Loss.

ABSTRACT:

Purpose

To quantify abnormalities in the peripapillary microvasculature in eyes with primary open-angle glaucoma (POAG) and paracentral visual field (VF) loss.

Design

Prospective, cross-sectional study.

Participants

Thirty-three POAG patients, including 15 with paracentral VF loss and 18 with peripheral VF loss, and 31 control participants underwent swept-source OCT angiography (OCTA) of the peripapillary region.

Methods

The POAG groups were matched by VF mean deviation (MD). The peripapillary microvasculature from the internal limiting membrane to the retinal nerve fiber layer (RNFL) interface was quantified within a 0.70-mm annulus around Bruch's membrane opening after removal of large vessels. Both vessel density (VD) and the integrated OCTA by ratio analysi

SUBMITTER: Nascimento E Silva R 

PROVIDER: S-EPMC8771989 | biostudies-literature | 2021 May-Jun

REPOSITORIES: biostudies-literature