Characteristics of circulatory failure after out-of-hospital cardiac arrest: a prospective cohort study.

ABSTRACT:

Background

Circulatory failure after out-of-hospital cardiac arrest (OHCA) as part of the postcardiac arrest syndrome (PCAS) is believed to be caused by an initial myocardial depression that later subsides into a superimposed vasodilatation. However, the relative contribution of myocardial dysfunction and systemic inflammation has not been established. Our objective was to describe the macrocirculatory and microcirculatory failure in PCAS in more detail.

Methods

We included 42 comatose patients after OHCA where circulatory variables were invasively monitored from admission until day 5. We measured the development in cardiac power output (CPO), stroke work (SW), aortic elastance, microcirculatory metabolism, inflammatory and cardiac biomarkers and need for vasoactive medicati

SUBMITTER: Langeland H 

PROVIDER: S-EPMC8772457 | biostudies-literature | 2022 Jan

REPOSITORIES: biostudies-literature