Application of fecal microbial transplantation in hepatic encephalopathy after transjugular intrahepatic portosystemic shunt.

ABSTRACT:

Rationale

Transjugular intrahepatic portosystemic shunt (TIPS) is mainly used to treat acute and chronic esophageal, gastric, and intestinal variceal bleeding and refractory ascites caused by portal hypertension. The most common complication of TIPS is the development of hepatic encephalopathy (HE). Fecal microbiota transplantation (FMT) is an emerging method for treating diseases by altering the intestinal flora. We present 2 cases of FMT that ameliorated liver function and HE after TIPS.

Patient concerns

In this report, 2 patients with liver cirrhosis secondary to hepatitis B had recurrent Grade 2-3 HE after TIPS.

Diagnosis

Two patients were diagnosed as having HE.

Interventions

The 2 patients separately received 3 times of FMT.

Outcomes

The liver func

SUBMITTER: Li J 

PROVIDER: S-EPMC8772766 | biostudies-literature | 2022 Jan

REPOSITORIES: biostudies-literature