Characterization of RNA Editome in the Mammary Gland of Yaks during the Lactation and Dry Periods.

ABSTRACT: The mammary gland is a complicated organ comprising several types of cells, and it undergoes extensive morphogenetic and metabolic changes during the female reproductive cycle. RNA editing is a posttranscriptional modification event occurring at the RNA nucleotide level, and it drives transcriptomic and proteomic diversities, with potential functional consequences. RNA editing in the mammary gland of yaks, however, remains poorly understood. Here, we used REDItools to identify RNA editing sites in mammary gland tissues in yaks during the lactation period (LP, n = 2) and dry period (DP, n = 3). Totally, 82,872 unique RNA editing sites were identified, most of which were detected in the noncoding regions with a low editing degree. In the coding regions (CDS), we detected 5235 e

SUBMITTER: Wu X 

PROVIDER: S-EPMC8773173 | biostudies-literature | 2022 Jan

REPOSITORIES: biostudies-literature