Mixed Depression: A Mini-Review to Guide Clinical Practice and Future Research Developments.

ABSTRACT: The debate on mixed states (MS) has been intense for decades. However, several points remain controversial from a nosographic, diagnostic, and therapeutic point of view. The different perspectives that have emerged over the years have turned into a large, but heterogeneous, literature body. The present review aims to summarize the evidence on MS, with a particular focus on mixed depression (MxD), in order to provide a guide for clinicians and encourage the development of future research on the topic. First, we review the history of MS, focusing on their different interpretations and categorizations over the centuries. In this section, we also report alternative models to traditional nosography. Second, we describe the main clinical features of MxD and list the most reliable assessment tool

SUBMITTER: Natale A 

PROVIDER: S-EPMC8773514 | biostudies-literature | 2022 Jan

REPOSITORIES: biostudies-literature