Energy Metabolism and Hyperactivation of Spermatozoa from Three Mouse Species under Capacitating Conditions.

ABSTRACT: Mammalian sperm differ widely in sperm morphology, and several explanations have been presented to account for this diversity. Less is known about variation in sperm physiology and cellular processes that can give sperm cells an advantage when competing to fertilize oocytes. Capacitation of spermatozoa, a process essential for mammalian fertilization, correlates with changes in motility that result in a characteristic swimming pattern known as hyperactivation. Previous studies revealed that sperm motility and velocity depend on the amount of ATP available and, therefore, changes in sperm movement occurring during capacitation and hyperactivation may involve changes in sperm bioenergetics. Here, we examine differences in ATP levels of sperm from three mouse species (genus Mus), diffe

SUBMITTER: Sansegundo E 

PROVIDER: S-EPMC8773617 | biostudies-literature | 2022 Jan

REPOSITORIES: biostudies-literature