A Brief Analysis of Proteomic Profile Changes during Zebrafish Regeneration.

ABSTRACT: Unlike mammals, zebrafish are capable to regenerate many of their organs, however, the response of tissue damage varies across tissues. Understanding the molecular mechanism behind the robust regenerative capacity in a model organism may help to identify and develop novel treatment strategies for mammals (including humans). Hence, we systematically analyzed the current literature on the proteome profile collected from different regenerated zebrafish tissues. Our analyses underlining that several proteins and protein families responsible as a component of cytoskeleton and structure, protein synthesis and degradation, cell cycle control, and energy metabolism were frequently identified. Moreover, target proteins responsible for the initiation of the regeneration process, such as inflammation

SUBMITTER: Ulhaq ZS 

PROVIDER: S-EPMC8773715 | biostudies-literature | 2021 Dec

REPOSITORIES: biostudies-literature