Efficacy and Safety of Immunotherapy for Cervical Cancer-A Systematic Review of Clinical Trials.

ABSTRACT:

Purpose

To systematically review the current body of evidence on the efficacy and safety of immunotherapy for cervical cancer (CC).

Material and methods

Medline, the Cochrane Central Register of Controlled Trials and Web of Science were searched for prospective trials assessing immunotherapy in CC patients in compliance with the Preferred Reporting Items for Systematic Reviews and Meta-Analyses guidelines. Full-text articles in English and German reporting outcomes of survival, response rates or safety were eligible.

Results

Of 4655 screened studies, 51 were included (immune checkpoint inhibitors (ICI) n=20; therapeutic vaccines n = 25; adoptive cell transfer therapy n=9). Of these, one qualified as a phase III randomized controlled trial and demo

SUBMITTER: Schmidt MW 

PROVIDER: S-EPMC8773848 | biostudies-literature | 2022 Jan

REPOSITORIES: biostudies-literature