Prediction of conserved and variable heat and cold stress response in maize using cis-regulatory information.

ABSTRACT: Changes in gene expression are important for responses to abiotic stress. Transcriptome profiling of heat- or cold-stressed maize genotypes identifies many changes in transcript abundance. We used comparisons of expression responses in multiple genotypes to identify alleles with variable responses to heat or cold stress and to distinguish examples of cis- or trans-regulatory variation for stress-responsive expression changes. We used motifs enriched near the transcription start sites (TSSs) for thermal stress-responsive genes to develop predictive models of gene expression responses. Prediction accuracies can be improved by focusing only on motifs within unmethylated regions near the TSS and vary for genes with different dynamic responses to stress. Models trained on expression responses i

SUBMITTER: Zhou P 

PROVIDER: S-EPMC8773969 | biostudies-literature | 2022 Jan

REPOSITORIES: biostudies-literature