Prospective examination of pre-trauma anhedonia as a risk factor for post-traumatic stress symptoms.

ABSTRACT:

Background

Anhedonia, the reduction of pleasure and reward-seeking behaviour, is a transdiagnostic symptom with well-described neural circuit mediators. Although typically observed during disease state, extant hypotheses suggest that anhedonia may also be an early risk factor for development of psychopathology. Understanding the contribution of anhedonia to the trauma-response trajectory may bolster inferences about biological mechanisms contributing to pre-trauma risk versus trauma-related symptom expression, knowledge of which could aid in targeted interventions.

Objective

Using a prospective, longitudinal design in a population at risk for trauma disorders, we tested the hypothesis that anhedonia may be a pre-trauma risk factor for post-traumatic stress disorder (PTSD) sy

SUBMITTER: Acheson DT 

PROVIDER: S-EPMC8774051 | biostudies-literature | 2022

REPOSITORIES: biostudies-literature