Potential Biomarkers for Post-Stroke Cognitive Impairment: A Systematic Review and Meta-Analysis.

ABSTRACT: Stroke is a primary debilitating disease in adults, occurring in 15 million individuals each year and causing high mortality and disability rates. The latest estimate revealed that stroke is currently the second leading cause of death worldwide. Post-stroke cognitive impairment (PSCI), one of the major complications after stroke, is frequently underdiagnosed. However, stroke has been reported to increase the risk of cognitive impairment by at least five to eight times. In recent decades, peripheral blood molecular biomarkers for stroke have emerged as diagnostic, prognostic, and therapeutic targets. In this study, we aimed to evaluate some blood-derived proteins for stroke, especially related to brain damage and cognitive impairments, by conducting a systematic review and meta-analysis and

SUBMITTER: Kim KY 

PROVIDER: S-EPMC8775398 | biostudies-literature | 2022 Jan

REPOSITORIES: biostudies-literature