The Role of Vitamin D in Diabetic Nephropathy: A Translational Approach.
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SUBMITTER: Delrue C
PROVIDER: S-EPMC8775873 | biostudies-literature | 2022 Jan
REPOSITORIES: biostudies-literature
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The Role of Vitamin D in Diabetic Nephropathy: A Translational Approach.
Delrue Charlotte C Speeckaert Reinhart R Delanghe Joris R JR Speeckaert Marijn M MM
International journal of molecular sciences 20220112 2
According to several animal and human studies, vitamin D appears to play a significant role in the development of diabetic nephropathy. However, the possible renoprotective effect of vitamin D and its influence on the reversal of already existing renal damage remains doubtful. At this moment, there are a few hypotheses concerning the underlying molecular and genetic mechanisms including the link between vitamin D and inflammation, oxidative stress, and extracellular matrix accumulation. The pres ...[more]
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