Petrobactin, a siderophore produced by Alteromonas, mediates community iron acquisition in the global ocean.

ABSTRACT: It is now widely accepted that siderophores play a role in marine iron biogeochemical cycling. However, the mechanisms by which siderophores affect the availability of iron from specific sources and the resulting significance of these processes on iron biogeochemical cycling as a whole have remained largely untested. In this study, we develop a model system for testing the effects of siderophore production on iron bioavailability using the marine copiotroph Alteromonas macleodii ATCC 27126. Through the generation of the knockout cell line ΔasbB::km^r, which lacks siderophore biosynthetic capabilities, we demonstrate that the production of the siderophore petrobactin enables the acquisition of iron from mineral sources and weaker iron-ligand complexes. Notably, the utilization of

SUBMITTER: Manck LE 

PROVIDER: S-EPMC8776838 | biostudies-literature | 2022 Feb

REPOSITORIES: biostudies-literature