Practical and Relevant Guidelines for the Management of Psoriasis: An Inference-Based Methodology.

ABSTRACT:

Introduction

Psoriasis (Pso) is a common, immune-mediated, chronic-relapsing, inflammatory skin disease. While a great deal is known about Pso and its treatment, there remain several treatment scenarios unaddressed by clinical studies. To be effective, treatment for Pso must alter the activity of one or more immunological pathways important in the pathogenesis of the disease. While the benefit of blocking these pathways may be apparent, there remain uncertainties regarding safety, such as infections, malignancies, and the potential for off-target effects. Existing guidelines and treatment recommendations rely primarily on clinical trial or observational data, none of which adequately address specific clinical challenges. This document describes a methodological framework for genera

SUBMITTER: Papp KA 

PROVIDER: S-EPMC8776962 | biostudies-literature | 2022 Jan

REPOSITORIES: biostudies-literature