FAM65A as a novel prognostic biomarker in human tumors reveal by a pan-cancer analysis.

ABSTRACT:

Background

Family with sequence similarity 65 member A (FAM65A), also known as RIPOR1, is differentially expressed between human tumor and non-tumor tissues in kinds of cancers. In addition, it was reported that the product of FAM65A may be a biomarker for cholangiocarcinoma patients. However, there is still no evidence on the relationship between the FAM65A and different types of tumors. Our study is mainly for exploring the prognostic values of FAM65A in pan-cancer and for further discovering a potential therapeutics target.

Methods

We analyzed FAM65A expression, prognostic values, genetic alteration, protein phosphorylation, immune infiltration and enrichment analysis across different types of human malignant tumors based on The Cancer Genome Atlas (TCGA) and Gene Express

SUBMITTER: Liang W 

PROVIDER: S-EPMC8777545 | biostudies-literature | 2021 Dec

REPOSITORIES: biostudies-literature