The impact of race on metabolic, graft, and patient outcomes after pancreas transplantation.

ABSTRACT:

Background

Racial disparities following pancreas transplantation (PTX) are poorly defined.

Methods

This was a large-scale, single-center, longitudinal cohort study including adult PTX recipients. Patients were grouped by race to allow for comparisons.

Results

287 PTX recipients were included; 125 (43.5%) were African American (AA). At baseline, AAs had a significantly higher proportion of T2DM (19.4% vs. 5.7%, p = 0.001), were younger, and more likely to be female. AAs experienced significantly higher rates of pancreatic leaks and post-operative bleeding. PTX rejection was comparable, however, kidney rejection tended to be higher among AA SPKs. Long-term mean HgbA1C levels were significantly higher among AAs (6.9% vs. 6.3%, p = 0.039). Patient and graft survival was c

SUBMITTER: Gonzales HM 

PROVIDER: S-EPMC8777579 | biostudies-literature | 2022 Apr

REPOSITORIES: biostudies-literature