Differentiation between Germinoma and Craniopharyngioma Using Radiomics-Based Machine Learning.

ABSTRACT: For the tumors located in the anterior skull base, germinoma and craniopharyngioma (CP) are unusual types with similar clinical manifestations and imaging features. The difference in treatment strategies and outcomes of patients highlights the importance of making an accurate preoperative diagnosis. This retrospective study enrolled 107 patients diagnosed with germinoma (n = 44) and CP (n = 63). The region of interest (ROI) was drawn independently by two researchers. Radiomic features were extracted from contrast-enhanced T1WI and T2WI sequences. Here, we established the diagnosis models with a combination of three selection methods, as well as three classifiers. After training the models, their performances were evaluated on the independent validation cohort and compared based on the inde

SUBMITTER: Chen B 

PROVIDER: S-EPMC8778008 | biostudies-literature | 2022 Jan

REPOSITORIES: biostudies-literature