Aptamers: Potential Diagnostic and Therapeutic Agents for Blood Diseases.

ABSTRACT: Aptamers are RNA/DNA oligonucleotide molecules that specifically bind to a targeted complementary molecule. As potential recognition elements with promising diagnostic and therapeutic applications, aptamers, such as monoclonal antibodies, could provide many treatment and diagnostic options for blood diseases. Aptamers present several superior features over antibodies, including a simple in vitro selection and production, ease of modification and conjugation, high stability, and low immunogenicity. Emerging as promising alternatives to antibodies, aptamers could overcome the present limitations of monoclonal antibody therapy to provide novel diagnostic, therapeutic, and preventive treatments for blood diseases. Researchers in several biomedical areas, such as biomarker detection, diagnosis,

SUBMITTER: Aljohani MM 

PROVIDER: S-EPMC8778139 | biostudies-literature | 2022 Jan

REPOSITORIES: biostudies-literature