A Systematic Approach for Developing 3D High-Quality PDMS Microfluidic Chips Based on Micromilling Technology.

ABSTRACT: In recent years, there has been an increased interest in exploring the potential of micro-and mesoscale milling technologies for developing cost-effective microfluidic systems with high design flexibility and a rapid microfabrication process that does not require a cleanroom. Nevertheless, the number of current studies aiming to fully understand and establish the benefits of this technique in developing high-quality microsystems with simple integrability is still limited. In the first part of this study, we define a systematic and adaptable strategy for developing high-quality poly(methyl methacrylate) (PMMA)-based micromilled structures. A case study of the average surface roughness (Ra) minimization of a cuboid column is presented to better illustrate some of the developed strategies. In

SUBMITTER: Javidanbardan A 

PROVIDER: S-EPMC8779272 | biostudies-literature | 2021 Dec

REPOSITORIES: biostudies-literature