Food Additives, a Key Environmental Factor in the Development of IBD through Gut Dysbiosis.

ABSTRACT: Diet is a key environmental factor in inflammatory bowel disease (IBD) and, at the same time, represents one of the most promising therapies for IBD. Our daily diet often contains food additives present in numerous processed foods and even in dietary supplements. Recently, researchers and national authorities have been paying much attention to their toxicity and effects on gut microbiota and health. This review aims to gather the latest data focusing on the potential role of food additives in the pathogenesis of IBDs through gut microbiota modulation. Some artificial emulsifiers and sweeteners can induce the dysbiosis associated with an alteration of the intestinal barrier, an activation of chronic inflammation, and abnormal immune response accelerating the onset of IBD. Even if most of th

SUBMITTER: Raoul P 

PROVIDER: S-EPMC8780106 | biostudies-literature | 2022 Jan

REPOSITORIES: biostudies-literature