High Throughput Identification of the Potential Antioxidant Peptides in Ophiocordyceps sinensis.

ABSTRACT: Ophiocordyceps sinensis, an ascomycete caterpillar fungus, has been used as a Traditional Chinese Medicine owing to its bioactive properties. However, until now the bio-active peptides have not been identified in this fungus. Here, the raw RNA sequences of three crucial growth stages of the artificially cultivated O. sinensis and the wild-grown mature fruit-body were aligned to the genome of O. sinensis. Both homology-based prediction and de novo-based prediction methods were used to identify 8541 putative antioxidant peptides (pAOPs). The expression profiles of the cultivated mature fruiting body were similar to those found in the wild specimens. The differential expression of 1008 pAOPs matched genes had the highest difference between ST and MF, suggesting tha

SUBMITTER: Tong X 

PROVIDER: S-EPMC8780859 | biostudies-literature | 2022 Jan

REPOSITORIES: biostudies-literature