Human Stem Cell Transplantation for Retinal Degenerative Diseases: Where Are We Now?

ABSTRACT: Background and Objectives: Irreversible visual impairment is mainly caused by retinal degenerative diseases such as age-related macular degeneration and retinitis pigmentosa. Stem cell research has experienced rapid progress in recent years, and researchers and clinical ophthalmologists are trying to implement this promising technology to treat retinal degeneration. The objective of this systematic review is to analyze currently available data from clinical trials applying stem cells to treat human retinal diseases. Materials and Methods: We performed a systematic literature search in PubMed to identify articles related with stem cell therapies to retinal diseases published prior to September 2021. Furthermore, a systematic search in ClinicalTrials (NIH U.S. National Library

SUBMITTER: Alcalde I 

PROVIDER: S-EPMC8781134 | biostudies-literature | 2022 Jan

REPOSITORIES: biostudies-literature