Sleep Disturbance in Individuals at Clinical High Risk for Psychosis.

ABSTRACT:

Introduction

Disturbed sleep is a common feature of psychotic disorders that is also present in the clinical high risk (CHR) state. Evidence suggests a potential role of sleep disturbance in symptom progression, yet the interrelationship between sleep and CHR symptoms remains to be determined. To address this knowledge gap, we examined the association between disturbed sleep and CHR symptoms over time.

Methods

Data were obtained from the North American Prodrome Longitudinal Study (NAPLS)-3 consortium, including 688 CHR individuals and 94 controls (mean age 18.25, 46% female) for whom sleep was tracked prospectively for 8 months. We used Cox regression analyses to investigate whether sleep disturbances predicted conversion to psychosis up to >2 years later. With regressions a

SUBMITTER: Zaks N 

PROVIDER: S-EPMC8781348 | biostudies-literature | 2022 Jan

REPOSITORIES: biostudies-literature