Ontology highlight
ABSTRACT:
SUBMITTER: Shin HJ
PROVIDER: S-EPMC8781396 | biostudies-literature | 2022 Jan
REPOSITORIES: biostudies-literature
Shin Hee Jae HJ Heo Chang-Su CS Anh Cao Van CV Yoon Yeo Dae YD Kang Jong Soon JS
Marine drugs 20220101 1
Four new streptoglycerides E-H (<b>1</b>-<b>4</b>), with a rare 6/5/5/-membered ring system, were isolated from a marine-derived actinomycete <i>Streptomyces specialis</i>. The structures of <b>1</b>-<b>4</b> were elucidated by detailed analysis of HRESIMS, 1D and 2D NMR data and ECD spectra as well as comparison of their spectroscopic data with those reported in literature. Compounds <b>1</b>-<b>4</b> showed significant anti-inflammatory activity by inhibiting lipopolysaccharide (LPS)-induced n ...[more]