Biocompatible and Thermoresistant Hydrogels Based on Collagen and Chitosan.

ABSTRACT: Hydrogels are considered good biomaterials for soft tissue regeneration. In this sense, collagen is the most used raw material to develop hydrogels, due to its high biocompatibility. However, its low mechanical resistance, thermal stability and pH instability have generated the need to look for alternatives to its use. In this sense, the combination of collagen with another raw material (i.e., polysaccharides) can improve the final properties of hydrogels. For this reason, the main objective of this work was the development of hydrogels based on collagen and chitosan. The mechanical, thermal and microstructural properties of the hydrogels formed with different ratios of collagen/chitosan (100/0, 75/25, 50/50, 25/75 and 0/100) were evaluated after being processed by two variants of a protoc

SUBMITTER: Sanchez-Cid P 

PROVIDER: S-EPMC8781623 | biostudies-literature | 2022 Jan

REPOSITORIES: biostudies-literature