Improving Care for Children with Bloody Diarrhea at Risk for Hemolytic Uremic Syndrome.

ABSTRACT:

Introduction

Children with infectious bloody diarrhea are at an increased risk for developing hemolytic uremic syndrome (HUS). Early intervention may improve outcomes. This study evaluated the impact of a clinical pathway designed to identify those at risk for HUS, guide initial management, and provide decision support regarding patient disposition.

Methods

We performed a retrospective cohort study of children 4 months to 19 years of age who presented with the acute onset of bloody diarrhea or other HUS risk factors to the pediatric emergency department (ED) from September 2015 through July 2020. A rapid stool polymerase chain reaction (PCR) test became available in May 2017. The clinical pathway was implemented in January 2018. We used Fisher's exact tests and statistical p

SUBMITTER: Burns CS 

PROVIDER: S-EPMC8782105 | biostudies-literature | 2022 Jan-Feb

REPOSITORIES: biostudies-literature