Diagnosis of human immunodeficiency virus associated disseminated intravascular coagulation.

ABSTRACT:

Introduction

Disseminated intravascular Coagulation (DIC) is a thrombotic microangiopathy which may complicate a number of severe disease processes including sepsis. Development of microvascular thromboses results in consumption of coagulation factors and platelets and ultimate bleeding. Patients with HIV infection (PWH) often present with baseline dysregulation of the coagulation system which may increase severity and derangement of DIC presentation. Previously, we have shown that HIV is a significant risk factor for development of DIC.

Methodology

We conducted a retrospective record review of all DIC screens submitted to our tertiary coagulation laboratory in Johannesburg, South Africa, over a one year period and compared the laboratory presentation of DIC in PWH with pres

SUBMITTER: Mayne ES 

PROVIDER: S-EPMC8782288 | biostudies-literature | 2022

REPOSITORIES: biostudies-literature