Ontology highlight
ABSTRACT:
SUBMITTER: Kotake K
PROVIDER: S-EPMC8782471 | biostudies-literature | 2022
REPOSITORIES: biostudies-literature
Kotake Kunihiko K Kumazawa Toshihiko T Nakamura Kiminori K Shimizu Yu Y Ayabe Tokiyoshi T Adachi Takahiro T
PloS one 20220121 1
In Japan, there is a long history of consumption of miso, a fermented soybean paste, which possesses beneficial effects on human health. However, the mechanism behind these effects is not fully understood. To clarify the effects of miso on immune cells, we evaluated its immunomodulatory activity in mice. Miso did not alter the percentage of B and T cells in the spleen; however, it increased CD69+ B cells, germinal center B cells and regulatory T cells. Anti-DNA immunoglobulin M antibodies, which ...[more]