Antibody levels and protection after Hepatitis B vaccine in adult vaccinated healthcare workers in northern Uganda.

ABSTRACT: Hepatitis B vaccine has contributed to the reduction in hepatitis B virus infections and chronic disease globally. Screening to establish extent of vaccine induced immune response and provision of booster dose are limited in most low-and-middle income countries (LMICs). Our study investigated the extent of protective immune response and breakthrough hepatitis B virus infections among adult vaccinated healthcare workers in selected health facilities in northern Uganda. A cross-sectional study was conducted among 300 randomly selected adult hepatitis B vaccinated healthcare workers in Lira and Gulu regional referral hospitals in northern Uganda. Blood samples were collected and qualitative analysis of Hepatitis B surface antigen (HBsAg), Hepatitis B surface antigen antibody (HBsAb), Hepatiti

SUBMITTER: Ocan M 

PROVIDER: S-EPMC8782524 | biostudies-literature | 2022

REPOSITORIES: biostudies-literature