Endoscopic Submucosal Dissection in North America: A Large Prospective Multicenter Study.

ABSTRACT:

Background and aims

Endoscopic submucosal dissection (ESD) in Asia has been shown to be superior to endoscopic mucosal resection (EMR) and surgery for the management of selected early gastrointestinal cancers. We aimed to evaluate technical outcomes of ESD in North America.

Methods

We conducted a multicenter prospective study on ESD across 10 centers in the United States and Canada between April 2016 and April 2020. End points included rates of en bloc resection, R0 resection, curative resection, adverse events, factors associated with failed resection, and recurrence post-R0 resection.

Results

Six hundred and ninety-two patients (median age, 66 years; 57.8% were men) underwent ESD (median lesion size, 40 mm; interquartile range, 25-52 mm) for lesions in the esophagus

SUBMITTER: Draganov PV 

PROVIDER: S-EPMC8783061 | biostudies-literature | 2021 Jun

REPOSITORIES: biostudies-literature