Evaluation by polymerase chain reaction assay of persistent shedding of pathogenic leptospires in the urine of dogs with leptospirosis.

ABSTRACT:

Background

Persistent leptospiruria in naturally infected dogs occurs despite appropriate antibiotic treatment.

Hypothesis/objectives

To determine the frequency of persistent leptospiruria in naturally infected dogs and the association of persistent leptospiruria with different antibiotic treatments.

Animals

Thirty-two dogs of varying age and breed diagnosed with leptospirosis via urine polymerase chain reaction assay (PCR).

Methods

A prospective observational study of dogs diagnosed with leptospirosis was undertaken to determine the frequency of persistent leptospiruria as determined by PCR. Clinical presentation of leptospirosis, antibiotic treatment, serum creatinine concentration, and outcome were recorded.

Results

Fifteen of 32 dogs had a negative u

SUBMITTER: Hetrick K 

PROVIDER: S-EPMC8783323 | biostudies-literature | 2022 Jan

REPOSITORIES: biostudies-literature