Serum cholinesterase may independently predict prognosis in non-small-cell lung cancer.

ABSTRACT:

Background

Serum cholinesterase (ChE) was found to be involved in cancer initiation and progression. However, the survival association between serum ChE and non-small cell lung cancer (NSCLC) has not been extensively discussed. In the present study, we aim to elevate the role of ChE in overall survival (OS) of NSCLC patients.

Methods

A total of 961 histologically confirmed NSCLC patients diagnosed between 2013 and 2018 in a provincial cancer hospital in southwestern China were retrospectively selected. Relevant information, such as histological type, clinical stage, chemotherapy, smoking status, body mass index (BMI), important serum indicators (albumin, neutrophil-to-lymphocyte ratio, ChE), date of death of the patients was extracted from the computerized hospital informati

SUBMITTER: Ran H 

PROVIDER: S-EPMC8783506 | biostudies-literature | 2022 Jan

REPOSITORIES: biostudies-literature