Single-level subject-specific finite element model can predict fracture outcomes in three-level spine segments under different loading rates.

ABSTRACT: Osteoporosis-related vertebral compression fracture can occur under normal physiological activities. Bone metastasis is another source of vertebral fracture. Different loading rates, either high-energy traumas such as falls or low-energy traumas under normal physiological activities, can result in different fracture outcomes. The aim of the current study was to develop a quantitative computed tomography-based finite element analysis (QCT/FEA) technique for single vertebral bodies to predict fracture strength of three-level spine segments. Developed QCT/FEA technique was also used to characterize vertebral elastic moduli at two loading rates of 5 mm/min, representing a physiologic loading condition, and 12000 mm/min, representing a high-energy trauma. To this end, a cohort of human spine se

SUBMITTER: Rezaei A 

PROVIDER: S-EPMC8783600 | biostudies-literature | 2021 Oct

REPOSITORIES: biostudies-literature