Increased admission serum total bile acids can be associated with decreased 3-month mortality in patients with acute ischemic stroke.

ABSTRACT:

Background

Bile acids (BAs) not only play an important role in lipid metabolism and atherosclerosis but also have antiapoptotic and neuroprotective effects. However, few studies have focused on the relationship of the total bile acid (TBA) levels with the severity and prognosis of acute ischemic stroke (AIS).

Objectives

The aim of this study was to investigate the potential associations of the fasting serum TBA levels on admission with the stroke severity, in-hospital complication incidence and 3 -month all-cause mortality in patients with AIS.

Methods

A total of 777 consecutive AIS patients were enrolled in this study and were divided into four groups according to the quartiles of the serum TBA levels on admission. Univariate and multivariate logistic regression anal

SUBMITTER: Huang L 

PROVIDER: S-EPMC8783998 | biostudies-literature | 2022 Jan

REPOSITORIES: biostudies-literature