Therapeutic effect of an ayahuasca analogue in clinically depressed patients: a longitudinal observational study.

ABSTRACT:

Rationale

Studies have suggested mental health improvements following the use of the psychotropic plant concoction ayahuasca in non-clinical and clinical samples.

Objectives

The present observational study assessed depressive symptomatology in 20 clinically depressed patients (symptom score > 13 on the Beck's Depression Inventory) before attendance of an ayahuasca ceremony and 1 month and 1 year after. Secondary measures included ratings of altered states of consciousness and ego dissolution during the ayahuasca ceremony as well as global measures of mindfulness, satisfaction with life, depression, anxiety, and stress.

Results

Twenty participants completed baseline and 1-day follow-up, 19 completed measures at 1-month follow-up, and 17 completed measures at 1-year fol

SUBMITTER: van Oorsouw K 

PROVIDER: S-EPMC8785027 | biostudies-literature | 2022 Jun

REPOSITORIES: biostudies-literature