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Aspirin thromboprophylaxis in joint replacement surgery.


ABSTRACT:

Background

Aspirin is commonly used as the only pharmacologic agent for prevention of venous thromboembolism (VTE) after joint replacement surgery in the United States. Despite this, prospective studies investigating VTE events after aspirin-only thromboprophylaxis in joint replacement surgery are lacking in the real-world setting.

Objectives

The aim of this study was to estimate the risk of VTE with aspirin-only pharmacologic prophylaxis following joint replacement surgery.

Methods

We carried out a prospective observational study of 350 low-risk patients (no prior history of VTE and low cardiovascular risk factors) who underwent total knee and total hip arthroplasty and received only aspirin for thromboprophylaxis postoperatively.

Results

The observed risk of

SUBMITTER: Sharda AV 

PROVIDER: S-EPMC8785144 | biostudies-literature | 2022 Jan

REPOSITORIES: biostudies-literature