Long-term effects of adolescent sport experience, DRD2 and COMT genes, and their interaction on sport participation in adulthood.

ABSTRACT:

Background

The present study investigated the joint impact of adolescent sport experience and dopamine-related genes (i.e., DRD2 and COMT genes) on sport participation in adulthood.

Methods

Using the National Longitudinal Study of Adolescent Health (Add Health) data, the hierarchical multivariable logistic regression models for predicting sport participation in wave 3 (around 20 years of age) and wave 4 (around 30 years of age) were conducted separately by gender (male and female) and gene (DRD2 and COMT genes).

Results

Adolescent sport experience significantly interacted with the number of DRD2 A1 alleles and COMT Met alleles in affecting wave 3 sport participation among male adults. The interaction between adolescent sport experience and DRD2 gene significantly affe

SUBMITTER: Lee CG 

PROVIDER: S-EPMC8785622 | biostudies-literature | 2022 Jan

REPOSITORIES: biostudies-literature