Estimating Kidney Failure Risk Using Electronic Medical Records.

ABSTRACT:

Background

The four-variable kidney failure risk equation (KFRE) is a well-validated tool for patients with GFR <60 ml/min per 1.73 m² and incorporates age, sex, GFR, and urine albumin-creatinine ratio (ACR) to forecast individual risk of kidney failure. Implementing the KFRE in electronic medical records is challenging, however, due to low ACR testing in clinical practice. The aim of this study was to determine, when ACR is missing, whether to impute ACR from protein-to-creatinine ratio (PCR) or dipstick protein for use in the four-variable KFRE, or to use the three-variable KFRE, which does not require ACR.

Methods

Using electronic health records from OptumLabs Data Warehouse, patients with eGFR <60 ml/min per 1.73 m² were categorized on the basis of

SUBMITTER: Naranjo FS 

PROVIDER: S-EPMC8786004 | biostudies-literature | 2021 Mar

REPOSITORIES: biostudies-literature