Patterned Illumination Techniques in Optogenetics: An Insight Into Decelerating Murine Hearts.

ABSTRACT: Much has been reported about optogenetic based cardiac arrhythmia treatment and the corresponding characterization of photostimulation parameters, but still, our capacity to interact with the underlying spatiotemporal excitation patterns relies mainly on electrical and/or pharmacological approaches. However, these well-established treatments have always been an object of somehow heated discussions. Though being acutely life-saving, they often come with potential side-effects leading to a decreased functionality of the complex cardiac system. Recent optogenetic studies showed the feasibility of the usage of photostimulation as a defibrillation method with comparatively high success rates. Although, these studies mainly concentrated on the description as well as on the comparison of single p

SUBMITTER: Diaz-Maue L 

PROVIDER: S-EPMC8787046 | biostudies-literature | 2021

REPOSITORIES: biostudies-literature