Spindle-Shaped Neurons in the Human Posteromedial (Precuneus) Cortex.

ABSTRACT: The human posteromedial cortex (PMC), which includes the precuneus (PC), represents a multimodal brain area implicated in emotion, conscious awareness, spatial cognition, and social behavior. Here, we describe the presence of Nissl-stained elongated spindle-shaped neurons (suggestive of von Economo neurons, VENs) in the cortical layer V of the anterior and central PC of adult humans. The adapted "single-section" Golgi method for postmortem tissue was used to study these neurons close to pyramidal ones in layer V until merging with layer VI polymorphic cells. From three-dimensional (3D) reconstructed images, we describe the cell body, two main longitudinally oriented ascending and descending dendrites as well as the occurrence of spines from proximal to distal segments. The primary d

SUBMITTER: Fuentealba-Villarroel FJ 

PROVIDER: S-EPMC8787311 | biostudies-literature | 2021

REPOSITORIES: biostudies-literature